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Studies indicate that ATP production is shifted towards glucose oxidation by Ranolazine
3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2
InChi: InChI=1S/C12H8Cl2N2O/c13-9-3-1-8(2-4-9)12(17)16-10-5-6-11(14)15-7-10/h1-7H
17-dien-8-yl]-2-oxoethyl 2-methylpropanoate
InChi: InChI=1S/C22H25N3O4/c26-18-4-1-5-19(28-11-13-6-7-13)20(18)17-9-15(14-3-2-8-23-10-14)16-12-29-22(27)25-21(16)24-17/h1
VX-661 Catalog No.:M10067-10 Studies indicate that ATP productionTezacaftor, also known asVX 661, is CFTR modulator. VX 661 is potentially useful for treatment of cystic fibrosis disease. Cystic fibrosis (CF) is a genetic disease caused by defects in the CF transmembrane regulator (CFTR) gene, which encodes an epithelial chloride channel. The most common mutation, 508CFTR, produces a protein that is misfolded and does not reach the cell membrane. VX 661 can correct trafficking of 508CFTR and partially restore
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